Unleashing the Immune System to Treat Pediatric Cancer

Immunotherapy is a type of biological therapy that utilizes the patient’s immune system to fight cancer. Over the last decade, immunotherapy has been proven as a viable treatment for a range of cancers. One form of immunotherapy, called CAR-T cell therapy, has shown a high level of success for leukemia and lymphoma patients. As you…


2022 Research Funded

Thanks to the support of generous donors, 28 projects have received funding for 2022. These projects address the widest range of pediatric cancers and represent the largest single-year financial support in the history of The Morgan Adams Foundation. This groundbreaking research has the potential to change the landscape for kids with cancer. The projects are…


What Donors Made Possible in 2021

Progress in medical research takes time — and it is only possible through funding and support of people who care. It can be difficult to wait for results. And that’s a million times harder if you know a child with cancer who needs a treatment that works right now. But progress IS happening. Advancements are…


Five new clinical trials for kids with cancer

Progress in medical research takes time – and requires sustained funding. Support for kids’ cancer research is critically important. Donations from caring individuals make possible studies into safer and more effective treatments for kids and teens. Without donor generosity, the good ideas doctors and researchers have would never make it out of the lab and into…


Using engineered immune cells to treat DIPG, a devastating brain tumor in kids

Using engineered immune cells to treat DIPG, a devastating brain tumor in kids Diffuse intrinsic pontine glioma (DIPG), also known as diffuse midline glioma, is a devastating type of pediatric brain cancer. The tumor is very aggressive and located deep within the brain, making it difficult to treat. The majority of DIPG tumors are caused…


Creating New Treatments for Kids with Craniopharyngioma

Craniopharyngioma is a type of pediatric brain tumor that typically affects kids under the age of 14 (although it also affects adults between 40-75 years). This tumor is unique in that it usually contains both solid and cyst-like components. Craniopharyngioma most often occurs at the base of the brain behind the eyes near the pituitary…


Moving personalized medicine forward for every child with cancer, at Children’s Hospital Colorado and beyond

Lia Gore, PhD Center for Cancer and Blood Disorders, Children’s Hospital Colorado Dr. Lia Gore is the Section Head for the Center for Cancer and Blood Disorders at Children’s Hospital Colorado. In addition to her role as the Section Head of Hematology / Oncology / BMT-Cell Therapy at Children’s Colorado, Dr. Gore is also the…


The evolution of genetic sequencing: from “chips” to RNA sequencing and single-cell analysis

Andrew Donson, Senior Research Associate The Morgan Adams Foundation Pediatric Brain Tumor Research Program at the University of Colorado Anschutz Medical Campus & Children’s Hospital Colorado Andy Donson has been an integral member of the research team since the lab first opened its doors more than 25 years ago. “I was a biochemistry major in…


Colorado researchers taking two-pronged approach in search for new AT/RT cancer treatments

Generally, there are two ways to discover a new cancer drug: You can use basic science to discover a cancer’s Achille’s heel and then find or build a drug that exploits it, or you can try a bunch of drugs on cancer cells and see what works. Think of the basic science approach as building…


Your support funds research to stop cancer treatments from causing more cancer

Children’s Hospital Colorado oncologist Adam Green, MD, understands the risks of whole-brain radiation, but sometimes it’s an important part of the cure for cancers like medulloblastoma or high-risk leukemia. The problem is that in addition to the long-term cognitive challenges that can accompany this use of radiation, the treatment can actually cause new cancers: About…