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2025 Funded Projects

  • Targeting an Oncogenic Driver in Infant Acute Lymphoblastic Leukemia: Bedside to Bench Correlative Studies

    Kelly Faulk, Patricia Ernst | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • A de novo map of the medulloblastoma transcriptome

    John Prensner | University of Michigan Medical School

  • Translating discoveries from brain tumor genomics into new therapeutic strategies

    David Solomon | Lucille Packard Children’s Hospital and Stanford University

  • Cell free tumor DNA burden, cell free tumor DNA Myc signature, and circulating tumor cell pharmacodynamics

    Brian Crompton | Dana-Farber Cancer Institute and Harvard University

  • Identification of the chromosome 1q oncogenic driver gene in posterior fossa ependymoma using functional genomic screening

    Nicholas Foreman | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Remodeling the immunosuppressive tumor microenvironment in pediatric ependymoma

    Nicholas Foreman, Andrea Griesinger | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Targeting cellular crosstalk mechanisms to develop novel treatment strategies for NF1-associated plexiform neurofibromas

    Nicholas Foreman | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Omics “in the round”

    Nicholas Foreman | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • BioInformatics support from Pluto

    Rajeev Vibhakar | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Improving B7H3 CAR-T efficacy in medulloblastoma

    Dong Wang, Rajeev Vibhakar | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Evaluation of KDM4B

    Bethany Veo, Rajeev Vibhakar | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Establish the efficacy of IDH1 inhibition in Myc amplified radiation resistant in vivo models

    Bethany Veo, Rajeev Vibhakar | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Single cell Resolution of ATRT

    Irina Alimova, Bethany Veo, Nathan Dahl, Rajeev Vibhakar | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Re-purposing an FDA-approved anti-malarial drug to treat DIPG, a fatal brain tumor in children

    Sujatha Venkataraman, Rajeev Vibhakar | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Pre-clinical testing the potential synergy between Radiotherapy and Gated CAR-T cell therapy against pediatric brain tumor

    Sujatha Venkataraman, Eric Kohler | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Pre-clinical Investigation to Support IIT of CDK7 inhibition in Pediatric Embryonal CNS Tumors

    Jean Mulcahy Levy, Bethany Veo | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Development of a novel CDK12 protein degrader model

    Nathan Dahl | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Targeting CDK11 in High Risk Neuroblastoma

    Raymond Walston, Nathan Dahl | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Combining Cellular Immunotherapy and Chemotherapy for the Treatment of Canine and Pediatric High-Grade Gliomas using Laboratory Comparative Oncology Techniques and a Canine Clinical Trial

    Adam Green, Mike Verneris, Steven Dow | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Investigation of Immunotherapy Approaches for Cancer Prevention

    Adam Green | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Investigation of tumor architecture and microenvironment evolution during relapse of pediatric brain tumors

    Adam Green, Nichaolas Foreman | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Incorporating radiotherapy and proteasome inhibition for high-risk pediatric brain tumors

    Nathan Dahl, Adam Green | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Determine the clonal progression of c-Myc medulloblastoma metastasis to the spine and forebrain through DNA barcoding

    Siddhartha Mitra | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Determine the unique immune microenvironment of EGFR mutant thalamic diffused midline glioma using In-Utero-Electroporation models

    Siddhartha Mitra, Santos Franco, Adam Green | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Validating Eye-Tracking for AI in Pediatric Tumor Diagnosis

    Todd Hankinson, Carsten Görg | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Characterizing and Cryo-Banking Adamantinomatous Craniopharyngioma Organoid Systems

    Todd Hankinson, Siddhartha Mitra | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • Validation of Patient Derived Xenograft Models of Adamantinomatous Craniopharyngioma

    Todd Hankinson, Siddhartha Mitra | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus

  • WillStrong Fund Scholar Award

    Matthew Witkowski | Children’s Hospital Colorado and University of Colorado Anschutz Medical Campus